Segunda sesión de entrenamientos libres del Gran Premio de Estados Unidos 2021
| Pos. | Piloto | Escuderia | Tiempo | Vueltas |
|---|---|---|---|---|
| 1 |  Sergio Pérez |
Red Bull | 1:34.946 | 24 |
| 2 |  Lando Norris |
McLaren | +0.257s | 20 |
| 3 |  Lewis Hamilton |
Mercedes | +0.364s | 22 |
| 4 |  Valtteri Bottas |
Mercedes | +0.414s | 24 |
| 5 |  Daniel Ricciardo |
McLaren | +0.511s | 21 |
| 6 |  Lance Stroll |
Aston Martin | +0.615s | 25 |
| 7 |  Charles Leclerc |
Ferrari | +0.626s | 23 |
| 8 |  Max Verstappen |
Red Bull | +0.878s | 23 |
| 9 |  Carlos Sainz Jr. |
Ferrari | +0.973s | 24 |
| 10 |  Antonio Giovinazzi |
Alfa Romeo | +1.192s | 26 |
| 11 |  Esteban Ocon |
Alpine | +1.212s | 23 |
| 12 | Pierre Gasly |
Alpha Tauri | +1.296s | 25 |
| 13 | Fernando Alonso |
Alpine | +1.430s | 18 |
| 14 | Kimi Räikkönen |
Alfa Romeo | +1.612s | 25 |
| 15 |  Sebastian Vettel |
Aston Martin | +1.772s | 30 |
| 16 |  Yuki Tsunoda |
Alpha Tauri | +2.037s | 24 |
| 17 | Mick Schumacher |
Haas | +2.095s | 24 |
| 18 | Nicholas Latifi |
Williams | +2.308s | 26 |
| 19 | George Russell |
Williams | +2.544s | 21 |
| 20 |  Nikita Mazepin |
Haas | +3.080s | 23 |