Segunda sesión de entrenamientos libres del Gran Premio de México 2021
| Pos. | Piloto | Escuderia | Tiempo | Vueltas |
|---|---|---|---|---|
| 1 |  Max Verstappen |
Red Bull | 1:17.301 | 28 |
| 2 |  Valtteri Bottas |
Mercedes | +0.424s | 31 |
| 3 |  Lewis Hamilton |
Mercedes | +0.509s | 26 |
| 4 |  Sergio Pérez |
Red Bull | +0.570s | 26 |
| 5 |  Carlos Sainz Jr. |
Ferrari | +1.017s | 29 |
| 6 |  Pierre Gasly |
Alpha Tauri | +1.128s | 29 |
| 7 |  Charles Leclerc |
Ferrari | +1.304s | 28 |
| 8 |  Yuki Tsunoda |
Alpha Tauri | +1.343s | 31 |
| 9 |  Sebastian Vettel |
Aston Martin | +1.380s | 32 |
| 10 | Fernando Alonso |
Alpine | +1.431s | 27 |
| 11 | Kimi Räikkönen |
Alfa Romeo | +1.540s | 25 |
| 12 |  Lando Norris |
McLaren | +1.678s | 27 |
| 13 |  Antonio Giovinazzi |
Alfa Romeo | +1.926s | 31 |
| 14 | Esteban Ocon |
Alpine | +2.130s | 37 |
| 15 |  Daniel Ricciardo |
McLaren | +2.220s | 7 |
| 16 | Mick Schumacher |
Haas | +2.319s | 30 |
| 17 |  Lance Stroll |
Aston Martin | +2.429s | 36 |
| 18 | Nicholas Latifi |
Williams | +3.519s | 17 |
| 19 |  Nikita Mazepin |
Haas | +4.280s | 28 |
| 20 | George Russell |
Williams | 2 |